If you'd asked most developers 5 years ago, most of them would have said: "Why would anyone want to write JS on the server?!" The luddites still do.
But we, at &yet, have fallen in love with node. Our particular schtick is the real-time web (see our podcast). We've been building real-time web apps for a while, mostly with XMPP and Strophe.js. Recently, however we've started using node + socket.io.
Frankly, we couldn't be happier and can't wait to see what the future holds as these technologies continue to mature.
We're humbled and excited to get to be a part of what promises to be an amazing conference. Given that it sold out in about 4 minutes, clearly we're not the only ones!
See you there!